Mustang does fly 'better' as in easier. More pleasant to fly? Not sure, it handles easier on t/o and landing, but airborne it borders to becoming boring! Compared to the spit that is
Greater range? How far do you want to fly?
Or, long do you want to be in cockpit?
A properly tuned Spitfire with a drop tank will last... well like over 90 minutes... I think? Fly from South English coast to Normandy, do some flying over there, get back home, no sweat.
The 109 I am not familiar with ...
(Tip: For real extra special fun in flying, get the I-16!)